No one's really sure how these drugs precisely work. They have different effects for different people, even if for things like depression and anxiety they nearly always offer improvement.
For something so elusive as DP/DR, their effects can vary. For some they help. For some they make it worse. For many, there's no change.
So the only answer I can really give is that it's perfectly "normal" for Zoloft to make DP/DR worse, since the effects it has in this area can vary. Some unfortunate folks, who were previously healthy, have got DP/DR just from taking these pills.
Don't worry about it, and stop or change medication if the problems with it continue.
I had mild anxiety when I was put on Zoloft. That is when the dp/dr started for me. I am not sure if it was a coincidence or if it was the Zoloft. The strangest part is that I wasn't depressed until I started taking an anti-depressant. It is so different for everyone, but that was my experience.
I was on Zoloft last summer and I had a great summer. I got off Zoloft in August 2004 cause I had to stop seeing the doctor I was seeing. Dumb move. I slipped back into depression terribly. I saw a new doctor in January 2005 and he started me back on Zoloft. I've had my good days and bad days. He had me up to 200mg, but I am now at 100mg because of the sexual side effects 200mg caused. I'm in a rut right now, but going to stick with the Zoloft. Again, like others have said, no one quite knows exactly what works. It's all trial and error and it's different for everyone. Unfortunantly, there is no one answer.
Paxil, which is a similar drug to zoloft, made me turn into a religious loon who wore long, golden crosses around my neck, put Jesus saves bumper stickers on my car, and condemned anyone who didn't believe what I did and sentenced them to an eternity of hellfire and brimstone. My vision also went to hell on these drugs. Everything seemed horribly distorted and fake. So yes, these drugs can make your dp worse and worst of all, they change who you are without you even realizing it.
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