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SSRIs and Depersonalisation

3358 Views 16 Replies 8 Participants Last post by  James_80
Hi all,

I'm writing cause I'm very curious about SSRI's and depersonalisation. I am curious as I have recently experienced 3 months of moderate to severe depersonalisation due to taking an SSRI (fluoxetine/Prozac). I won't go into to details about the story, but it was a series of mistakes made by doctors failing to listen and understand that got me into that situation. Thankfully since stopping the medication the symptoms have been dissipating over the last month. Obviously, DP was a million times worse than the initial anxiety that was having and was not worth the DP to cure. I am very glad that the DP is going away slowly but this whole experience has left me quite scared of SSRIs. I have used them in the past and they helped to cope with the anxiety and stop it limiting my life. I would like to take an SSRI or some other medication for anxiety, but I never want to go back to that place again (depersonalisation) and not be able to get out. I have read several stories of people on here that claim an SSRI caused their DP and it never went away. So, my question is, is this a reasonable fear?

I can find no scientific literature on SSRI's causing permanent DP and the other medications that cause DP such as Minocyline, the symptoms resolve themselves slowly on cessation of the medication, as in my case. I want to understand what people are experiencing when they claim that the SSRI caused their DP? Is this actually a real thing? SSRIs have been on the market since the 1980s and millions of prescriptions are written each year and there is no published evidence that they are linked to permanent depersonalisation. If anyone who has any insight/personal experience or knows anything I could read that might help me understand this, it would be greatly appreciated. Also if anyone know about other medications causing DP could they please let me know.

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I wouldn't get yourself worried about this being permanent for you. Your symptoms have improved since stopping the meds which is a great sign.

You can google anything and find someone who had it. It does happen it seems but is very rare, and I would still say for some of those people it is more likely a sign of anxiety. And then because they don't see a health professional who can reassure or explain it to them this makes the anxiety worse. And you have the anxiety > symptoms feedback loop and then the symptoms become the stressor and people get stuck.

Just focus on relaxing and not seeing the symptoms as a threat. Just a sign of a tired body/mind that needs some rest. I am sure it will continue to pass with time for you
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