i am very much into natural healing.i have not even taken an aspirin in over 10 years. from what i have heard it really has to do with b vitamins and adrenals.it really makes sense to me. i read about Victor Frankl and desoxycorticosterone, which is an adrenal hormone, and how it snapped people out of dp/dr.the drug name for it is Percorten, but i looked it up and licorice stimulates the body to produce it.i also believe sugar makes it worse.i have talked to a psychiatrist that recommends supplements for her patients and she recommends what she calls a "depression coctail", which is several specific Mannatech supplements taken throughout the day.she has a 90+percent success rate with her patients.i also believe every person is different and there are probably many reasons people get dp/dr.