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Discussion Starter · #1 ·
Today i made a quantic EEG and for the first time they found a dysfunction in my brain and i got a objectification for my subjectiv felt numbness. They found in my brain a complete dissociation of network especially in emotion and awareness. I have abnormalities at left prefrontal cortex and my complete right side which included the area of insula. My mirror neurons are deactivated, the connection to my amgydala area is deactivated and i have an overload connection to observation, which seems to block all other brain assiociated functions. My brain seems to be in a permanent and artificial default network modus. After my long research for reasons i didnt thought to find anything even in quantic EEG.

The next day i will get detailed results and inform you.

Maybe for all of you it could be interesting to do a quantic EEG (when you can pay it and it is offering in your region) to get an objectification for your suffering
 

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That is in line with the front-limbic model of depersonalization. The frontal lobe inhibits that amygdala, insula and areas related to emotions and make a state of immobilization. It is related to overregulation in response to fear and anxiety. The problem with fMRI scans and qEEG is that the locations are often diffuse. The prefrontal cortex is a large area with many locations. Most models point to the medial prefrontal cortex both left and right as central in making a suppression of fear and anxiety. The should also be connections from there to the brain stem. The brain stem has until recently been difficult to scan as it is deep and structures are very close to each other. In the dissociative subtype PTSD is was found the a structure called PAG/periaqueductal Gray was active in the ventral part in dissociative states while the dorsal part was active in those with a fight and flight response. So, in goes deep into the brain and activate very old structures and responses. The anterior cingulate is also active in depersonalization and is as deep in the brain as the medial prefrontal cortex. The medial prefrontal cortex Is a central hub in the default mode network. The brains resting and self reflection stare. So, it is not normal in depersonalization.

In theory rTMS could inhibit this network response but these locations are to deep for a normal rTMS to affect. You need a special coil to do rTMS or you could use a special design H-coil for the disorder for deep TMS like "Brainsway". Their coil for OCD should affect the medial prefrontal cortex and anterior cingulate. But, I don't think it has been tried. A model for dissociative PTSD here,

https://jmvfh.utpjournals.press/doi/pdf/10.3138/jmvfh.2019-0031
 

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Discussion Starter · #5 ·
To saibon:

i am 52 old and i got from it weed cookies

to mayer-gross:

i know all the theories of brain function in dp not at least from you, but as i saw it in my brain on monitor and graphics that i have abnormalities makes it concrete and not only a theory. sure its only diagnostic and it dont change any in treatment. the doc works with neurofeedback, tdsc and other wave techniques...maybe some of them can change something
 

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Ok. Tdsc might be able to affect the medial prefrontal cortex. It is the right that is thought overactive in many models.

No, I have not thought of qEEG or brain scans. I can see on the existing scan where there have been both a large patient group and a large normal control group to compare with that it difficult to see where it starts -many areas are over or under active. They have difficulty in finding where it starts. If I did something similar, data would likely be close to them. It might make sense if they knew much more about the disorder and the locations. Some patients might differentiate in the areas and networks mobilized in the prefrontal cortex as it's the case in depression. Then you could say that you are in the group, your regulation comes from that area and to start rTMS at this location and drop the other might be the best. You can not do that today. The other problem is, -are you able to intervene in those areas.
 

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A qEEG might be useful however for those on this forum suffering from emotional numbing without disembodiment symptoms. In these cases it’s impossible to know if the emotional numbing is caused by depersonalization disorder. If a qEEG shows a neurobiological model closer to those in the patient group of DP studies, then it is more likely that it is Depersonalization disorder that is causing their symptoms.
 
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