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Hi everyone. I realise that psychedelics are the reason that some of you may have developed dp. In my case it wasn't. Pure anxiety and depression and (possibly) trauma that I'm not even consciously aware of. I have always had a strong interest in psychedelics and read about them a lot and feel a calling to try them out responsibly but, obviously with being prone to dp, I am cautious about this. It would have to be done in a therapeutic environment for me to feel as confident as possible that I could pull through with maximum benefit and minimum risk. My dp has been there for as long as I can remember although sometimes it almost completely goes and stays like that for years. My feeling about dp now is that it isn't something that I am scared of anymore and is more of an annoyance and a hindrance to living life to the full. The main issue for me is being stuck in depression a lot of the time and stuck in a rut. I feel lost and directionless to be honest in my life. I can use the well known techniques to reduce my feelings but I never ever get to that sweet spot of actually enjoying life and not feeling like some sort of failure. This is where my interest in psychedelics, especially mushrooms, come in. They are meant to be effective for people stuck in treatment resistant depression and can help deal with trauma and general anxieties about life. I feel a strong calling to try them. I have heard of people using them and it cleared their dp up. I have also heard horror stories too. What are people's feelings on them?
 

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I used magic mushrooms to hopefully cure me of my depression and anxiety. A lot of people fussed how shrooms could do that. But guess what, I did not get cured of depression and anxiety, but I also got dpdr now.
It is a risk to use shrooms in treating psychological conditions. There is no assurance they will.
Was it all bad? No. Shrooms have also helped me in discovering a few things about myself. When I was on high I felt emotionally invulnerable, unusually confident. But these effects are as temporary as the high the shrooms can induce. At the end of the day, you have to learn these things the hard way to make then permanent.
I am more on the side of no in using shrooms because the risk is greater than the positive effects, I say this with all seriousness. But if you still want to proceed, do with caution and knowledge.
 

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I went down this path a while back. Am tempted to revisit it at some point. It has had amazing effects with depression and PTSD and I really hope therapy gets legalised soon. I did it alone at home and the experience was pretty amazing, but it also makes you pretty sick before you trip. My last experience had me feeling very sick and I stood over the toilet to vomit. Before I knew it I woke up later on the floor, I had fainted before I could vomit (weirdly this is how my DP started).

Take a lot of caution and trip with someone you trust if you can. Ideally a therapist, there are some underground but I couldn't find any as they are understandably hard to find. Good luck and let us know how it goes if you go ahead with it
 

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How did your dp start? Was it through taking mushrooms?

I hope it's legalised too if it's true that it has helped so many out of depression and ptsd. They are doing trials on it at the moment. I put myself on the list but I doubt I will get selected as its first come first served. Hundreds have applied. Here is the link to the trials:

https://www.kcl.ac.uk/ioppn/depts/pm/research/cfad/psilocybin-trials

In the meantime I'm continuing with trying out the Wim Hof breathing method and cold showers. Positive results so far. With a bit of luck I won't need to try anything else.
 

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I've never done any drugs more potent than weed. But I still have to weigh in here. To my understanding, if you are experiencing existential issues--feeling directionless, etc.--I'm not sure how shrooms will help with that type of problem. The experience people have on them I'm told can be enjoyable, but it is just that, an experience. Like going to an amusement park, it can be a thrilling trip, but I don't see how it will give you any direction in life or offer many benefits extending beyond the experience itself. I could be wrong, of course, but if it were me, I'd probably not risk it. Seems like the potential negative probably far outweigh the positives.
 

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I've never done any drugs more potent than weed. But I still have to weigh in here. To my understanding, if you are experiencing existential issues--feeling directionless, etc.--I'm not sure how shrooms will help with that type of problem. The experience people have on them I'm told can be enjoyable, but it is just that, an experience. Like going to an amusement park, it can be a thrilling trip, but I don't see how it will give you any direction in life or offer many benefits extending beyond the experience itself. I could be wrong, of course, but if it were me, I'd probably not risk it. Seems like the potential negative probably far outweigh the positives.
I totally agree. I had dpdr from using shrooms. I wanted to be happy that's why I used shrooms. But I didn't and just had dpdr. For me the use of psychedelics is just the imagination that there is a shortcut. There's not.
 

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I'm a believer of the 2nd law of thermodynamics. That is the law of entropy, which states that things tend to disorder. In other words, why would you ingest a psychoactive drug which is akin to throwing your mind into the air, and expect it to land in better order

than when you tossed it? I don't know where you get your information "(mushrooms) are meant to be effective for people stuck in treatment resistant depression". Really? Well, the world needs more psychonauts. Take a big dose and report to Erowid.com.

They are keeping score.
 

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I'm a believer of the 2nd law of thermodynamics. That is the law of entropy, which states that things tend to disorder. In other words, why would you ingest a psychoactive drug which is akin to throwing your mind into the air, and expect it to land in better order
than when you tossed it? I don't know where you get your information "(mushrooms)

are meant to be effective for people stuck in treatment resistant depression". Really? Well, the world needs more psychonauts. Take a big dose and report to Erowid.com.​

They are keeping score.​
I hoped there was a like button. I believed what they said shrooms could cure depression, google searches seemed to agree. Now im on this forums talking about dpdr.
 

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Another thing that shows big promise is ecstasy therapy. Unfortunately we dont know how big the risks are with these type of things though. We can say with confidence that anti depressants generally help but they aren't without their risks (suicidal thoughts, erectile disfunction, weight gain). But we also know the risk:reward ratio is pretty high. The problem is we don't know who is going to have a horror story with these drugs and what predisposes people to react badly.

I think in Holland there are even ecstasy clinics but I am not sure about this. As there are clinics in Europe for ibogaine. I wouldn't ever recommend any of these to anyone though. Do a lot of your own research and consider the risks. To me if I had to put money on it, ecstasy seems safer. Professor David Nutt (uk government advisor for drug safety) famously was fired for saying ecstasy was safer than horse riding. He wasn't advocating the use of drugs, just objectively stating the risks compared to something we consider relatively safe. The harm with ecstasy usually comes from drinking too much water and people over hydrate and die. Again it has other risks like psychosis. Were these people already at risk? Are there larger risks if we already have a dissociative disorder? Maybe. Science is scarce unfortunately but I may well try ecstasy therapy one day... purely out of desperation as nothing conventional really helps
 

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According to the US National Institute of Health, ECT is a highly effective treatment for treatment resistant depression. A group of 38 patients with treatment resistant depression received at least

6 sessions of ECT. Half had their depressive episodes end. 65% reported significant improvement. I didn't see any studies where the NIH reported

"shrooms" to be an effective treatment for depression. One has to consider the source when evaluating claims made by unnamed sources.

For example: "especially mushrooms...... They are meant to be effective for people stuck in treatment resistant depression"
 

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Discussion Starter · #11 ·
According to the US National Institute of Health, ECT is a highly effective treatment for treatment resistant depression. A group of 38 patients with treatment resistant depression received at least

6 sessions of ECT. Half had their depressive episodes end. 65% reported significant improvement. I didn't see any studies where the NIH reported

"shrooms" to be an effective treatment for depression. One has to consider the source when evaluating claims made by unnamed sources.

For example: "especially mushrooms...... They are meant to be effective for people stuck in treatment resistant depression"
OK, you can replace the word "meant" with "might". Might be effective for treatment resistant depression.

Kings College London are currently running trials on psilocybin. There is lot of information on the history of psilocybin use on that page: https://www.kcl.ac.uk/ioppn/depts/pm/research/cfad/psilocybin-trials

Two further studies are referred to in this article that psilocybin "demonstrated immediate and marked reductions in their levels of anxiety and depression": https://www.independent.co.uk/voices/psychedelic-drugs-lsd-magic-mushrooms-new-study-psychiatry-mental-illness-terminal-cancer-patients-a7449331.html
 

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From one of the above studies: "feelings of isolation, depression and anxiety commonly associated with a diagnosis of terminal illness."

I'm not satisfied the above patients can be considered as treatment resistant depression. If I were diagnosed with terminal illness,

I would quite naturally be depressed about it. I think that is significantly different than being mentally ill with major depression.
 

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From one of the above studies: "feelings of isolation, depression and anxiety commonly associated with a diagnosis of terminal illness."

I'm not satisfied the above patients can be considered as treatment resistant depression. If I were diagnosed with terminal illness,

I would quite naturally be depressed about it. I think that is significantly different than being mentally ill with major depression.
That is a good point actually. It really gets on my nerves when I see lazy diagnoses of depression given for things like that, when depression, as you know, is a separate illness entirely. Nevertheless, I am hoping psilocybin proves useful for cases of depression that are caused or influenced by trauma. I think there are cases of depression caused primarily by physical factors such as inflammation in which case I am guessing psilocybin would not be an effective long term solution.
 

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Hey. I have tryed taking "Psilocybe Cubensis" with dp, i took 2.5g. My friend took same amount, he had a more visual experience, not sure if the dp is making you trip less or if my shrooms were abit less potent or if hes more easily affected by it. I have taken another simillar mushroom before dp and then everything moved around smaller bigger, nice emotions etc etc. This time i barely had anything visual, slight change and a big thought process going on, i felt some weird sensations in my body aswell, was nice for a change. But this dosage did nothing for me sadly. With a bigger dose maybe it would, or could make it worse, unsure! Its a risk, think about the pros and cons before doing it, alot of people like to tell you not to take them. But waiting it out, meditation, eating healthy etc dosent seem to do much for many of us. Think alot about it and do what you think is the best thing for you to do..

I have also tryed drinking while having dp, dosent help me anything, it helps me to stop care about it, i can more easily fake that im happy but i get no emotions or anything. I have smoked weed aswell, just makes me think way more than normal. I have tryed benzos aswell, they make me care less about everything. I have also tryed "Laughing gas", not sure if thats what its calld, didnt do anything, felt like i got deeper into dp after doing that, sooner i realized it was a dissociative drug, im so smart.. I kinda did it out of frustration because im so sick of it, so i took the chanse. Wouldnt recommend any of theese exept maybe mushrooms. Im not sure how its going to affect you in highier doses, LSD is also intresting and ofc DMT but DMT feels quite risky to do..

I think Mushrooms, MDMA, LSD, DMT could possibly flip the switch somehow, but theres for sure a high risk to it, thats why i havent tryed them.

Not sure if you got anything out of my ramble here but think alot about it, read up, try everything you can before doing any drugs and after that, if nothing helps and it feels right, possibly try something in safe and prepared settings! Goodluck, hopefully we can go back to being normal before we die, would be nice..
 

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Personally, I’ve always been terrified of psychedelics. Part of this is because I was out with myself friends one night smoking a shit ton of bud while my friends also took shrooms. Long story short my one buddy, who had done it a few times before, got severely dehydrated and had a seizure and fell right into my arms. It was terrifying. I guess moral is stay hydrated and be in A comfortable environment with people you can trust if you’re to take psychedelics.
 

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The brain is so complicated and sensitive. The blood brain barrier is designed to protect brain function by forbidding entry to foreign things. Psychedelics and THC can get in, imitating neurotransmitters and creating distorted or false sensory perceptions and emotions.

Its all fun and games, until your brain decides it must attempt to adapt and tune into these fake and distorted sensory perceptions. In doing so, it discards the old normal. Is it possible to use psilocybin to tune into a new normal ? Maybe. But it sounds like a real crap shoot to me. Psychological experiences can activate genes

or switch them off. I have a theory about those who report having panic attack, and then having their dp/dr begin a day or two later. It's a story I've heard fairly often on this forum. Say you have a traumatic experience on a psychoactive drug. Your system responds by switching off

a gene, and its function. If you switch a gene off, it stops producing the proteins that support that given function. Your system now has a limited existing supply

of those proteins to continue the function.....for a day or two. Then, you have exhausted the remaining proteins and the function ceases. You are now in your new reality absent that function.

I got this idea from an Incident in my past. A good friend's apartment exploded in a gas leak. He was burned very badly. I saw him and he looked good and was positive about recovery.

I had been playing racquetball with a neurologist and told him about my friend. He asked what % he was burned. I said 85%. He said "he won't make it.". But, I just saw him and

he looked great. Well, he says....the skin is an organ. You burn that much and you can live on your reserves for a few days. Then, you dive down and out. Which, my friend, sadly, did.

I'll just add this about the genome. Huge sums of cash are donated to Cancer research, kidney foundation, this illness and that disease. That funding stream has to change. It has to be redirected to

genetic research. The genome is everything. It governs the processes by which we live day to day.Genetic research can provide all the answers. It is now providing the answers that oncology and other sciences were never going to figure out for themselves.

But, people are funny when it comes to money. It is not going to be easy to redirect the funding from the diseases, to the underlying causes of those diseases.
 

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At this point, other than some herbs or supplements (which probably don't do anything at all). I'm not putting any more "medicine" in my body, or performing any more corporal interventions unless/until I find at least some evidence of what is actually wrong, if anything with my brain, and that the intervention in question has been demonstrated to help ameliorate the issue in question.
 

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I'm of the opinion it is very risky and there chance to stuck like this...till the day you will die. On other hand all these drugs have some ilusive potential to help us. Personally I think about cannabinoids. Want to try wild weed without THC but with some amount of cannabinol (not CBD) and see what happens. No risk only experiment.
 

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Why CBN? Had a quick search but couldn't find much of what it does, other than is a partial agonist of CB1 and CB2 like THC but weaker. Apparently THC degrades to CBNA in ultraviolet light so you could technically grind skunk and leave it in the sun for a while (no idea how long or how effective that would be though).

CBD has helped me relax and sleep a bit better, which aren't bad things. Unfortunately hasn't really helped the DP yet... but may in the long run
 
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