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NEW RESEARCH (Sept. 16, Nature)

2974 Views 15 Replies 6 Participants Last post by  forestx5
New research has just been released that examines dissociation from a novel perspective. The large group of researchers claim to have found the root of all dissociation, not just in humans, but across "all species". These findings are profound:

  • "The rhythmic activity of a single layer of neurons has now been shown to cause dissociation - an experience involving a feeling of disconnection from the surrounding world."
  • "Vesuna and colleagues' work provides compelling evidence that a low-frequency rhythm in the deep posteromedial cortex is an evolutionarily conserved mechanism that underlies dissociation across species." [link]

https://www.nature.com/articles/d41586-020-02505-z?fbclid=IwAR05h0g3b7sviaFdQlzi6eieFzRMpwj_1i3AksJYbq-7Y632jvV-4AoVMJY
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"Such studies should also include medicines, such as benzodiazepines and Lamotrigine, that attenuate Ketamine-induced dissociation. "

That's a very interesting sentence. I don't know how long I persevered with Lamotrigine but perhaps I should try again. I noticed absolutely no effect and got up to a relatively high dose in the end.. never had the chance to really try a benzo properly. Just a shitty low dose Diazepam.

Interesting article. Someone posted a recovery story recently and said they partly had relaxation to thank. Anxiety > adrenaline > fight/flight/freeze. Freeze is dissociation I believe with is Physiologically speaking, tension trapped in the muscles. Would be interesting
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The retrosplenial cortex seems a pretty fascinating area I hadn't really considered but seeing just basic info about it explains many symptoms of my individual DPD. Particularly episodic memory.. I have some form of dissociative amnesia. I just shut down when challenged, or embarrassed socially.

Dont know what this could hold, looks promising as a new idea though. Has made me consider trying Lamotrigine again. I know one person said they felt nothing for months once, then it was as if one day a lightbulb was switched on... Benzo's in small doses perhaps. Perhaps Clonazepam, although unlikely my GP will prescribe me that
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