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My naloxone trial

5519 Views 37 Replies 5 Participants Last post by  teal
I've got six Nyxoid nasal sprays, each containing 1.8 mg naloxone. I used the first of them today, eight minutes ago. To get a smaller dose, I blew my nose right after taking the first dose. Got five more doses left for later.

Why try? In the British Journal of Psychiatry they write.

Nuller et al(2001) found a significant transient beneficial effect of naloxone infusion on symptoms of depersonalisation in 10 of 14 patients studied. This intriguing result suggests a possible role of the endogenous opioid system in the pathogenesis of depersonalisation, and the possibility that anti-opioid drugs may have therapeutic value. To date, this hypothesis has not been explored further in the literature, despite the impressive results from this pilot study.
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There has been a "studies" with "trials" of lamotrigine with a high response rate and reductions that has been retracted because they where fraud. People do post here with reference to it despite it is openly retracted.
This study claims a really high response rate. Do we know why it was retracted?
I think it is all made up.
Definitely a suspicious trial, but why would anyone be interested in publishing fake information to the public, especially when it concerns such a delicate field of research?
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