Depersonalization Support Forum banner

My naloxone trial

5517 Views 37 Replies 5 Participants Last post by  teal
I've got six Nyxoid nasal sprays, each containing 1.8 mg naloxone. I used the first of them today, eight minutes ago. To get a smaller dose, I blew my nose right after taking the first dose. Got five more doses left for later.

Why try? In the British Journal of Psychiatry they write.

Nuller et al(2001) found a significant transient beneficial effect of naloxone infusion on symptoms of depersonalisation in 10 of 14 patients studied. This intriguing result suggests a possible role of the endogenous opioid system in the pathogenesis of depersonalisation, and the possibility that anti-opioid drugs may have therapeutic value. To date, this hypothesis has not been explored further in the literature, despite the impressive results from this pilot study.
  • Like
Reactions: 1
1 - 1 of 38 Posts
This is really interesting. What were the effects after taking it? I have thought of trying this myself but wouldnt know how to get hold of it. How did you get it in the uk? I will follow this thread am really intrigued to see how it goes
1 - 1 of 38 Posts
This is an older thread, you may not receive a response, and could be reviving an old thread. Please consider creating a new thread.
Top