[Funky Buddha]

Hello,

Basically, their is a new drug that has been developed for Depersonalization / Derealization symptoms but it can only be synthasised if enough people decide to go through with buying it. It's still a research chemical at this stage but if more people decide to take interest over at Longe City then this stuff will be made and will help with your symptoms, and could even get rid of them completely. In fact it was made for Depersonalization / Derealization.

Take a look here about the chemical:

http://en.wikipedia.org/wiki/JDTic

Go here if you are interested, then you can join the forum and let them know that you want to be part of the group buy so you can get this stuff. That's if enough people decide they want it.

http://www.longecity.org/forum/topic/63691-jdtic-kappa-antagonist-bulkgroup-buy/

If there are any questions you would like answered then just let me know, or post a question on the forum...

Thanks for looking.

 

[odisa]

I concur; this is currently the best chance at having a proper pharmacological treatment for DP.

The reason Naloxone and Naltrexone have been used is for their Kappa Opioid Receptor antagonism; these have proven beneficial, with Naloxone completely abolishing symptoms in a portion of patients. Problem is that Naltrexone and Naloxone also antagonize other opioid receptors, then there's Naloxone which has to be administered intravenously, and Naltrexone tends not to be tolerable at dosages where it antagonizes the KOR sufficiently.

I made a post here explaining a bit more, though the Longecity thread explains it in more detail.

 

[missjess]

I concur; this is currently the best chance at having a proper pharmacological treatment for DP.

The reason Naloxone and Naltrexone have been used is for their Kappa Opioid Receptor antagonism; these have proven beneficial, with Naloxone completely abolishing symptoms in a portion of patients. Problem is that Naltrexone and Naloxone also antagonize other opioid receptors, then there's Naloxone which has to be administered intravenously, and Naltrexone tends not to be tolerable at dosages where it antagonizes the KOR sufficiently.
I made a post here explaining a bit more, though the Longecity thread explains it in more detail.

Have u actually taken this substance urself?

 

[odisa]

Meh. The heart issues seem rather benign, moreover transient. Essentially a non-issue IMO.

Not yet missjess, but I plan to.

 

[Funky Buddha]

The heart issues have only been recoded on one person. I have, however tried Salvia divinorum which also causes Ventricular tachycardia and have had no issues with it. Just make sure you start of with a very low dose of this stuff, I don't really know at what dose this stuff is active at but I can tell you if it's anything like salvia without the hallucinations then I'll be very happy indeed. That stuff blew my anxiety / depression away.

You can read more about it here

http://jdtic.com/

It's to prove that it's safe and that it has been in trial sinse 2011. I would think it's advisable to get your blood pressure / health checked first though just incase you have high blood pressure or something. We will keep you posted if we find anymore human trials.

I have severe Major Depression [ed: PHQ-9 score of 22]. I have Anheodnia, no emotions, very few
feelings, and avoliton. I have severe anxiety. I can hardly speak. I only
answer questions. I do not engage in social conversations because of my severe
thought poverty and inability to process the emotional content in
conversations. I feel frozen, numb and tortured. I have to work confused,
severe memory probelms, trembling and just really screwed up. My life is a
nightmare every day of my life.

I received the JDtic one afternoon. I was so eager to try it I
divided the jdtic into 2mg dosages and put it into capsules. I tried my first dose
that afternoon. The next day I woke up feeling this really warm, clean, healthy
feeling. I felt completley free of anxiety. I kept having involuntary erections for
no reason. I never have an erection for anything. I started watching the television
and I started to have a warm feeling in my stomach from watching my favorite show. I
started to get all these feelings from my body that I never get. I started to get
cold chills from watching a movie. I started to have hunger pains. I never feel
hungry. I walked outside. The breeze felt so good that day. When I went to work. I
looked at people in the face and spoke to them without feeling frozen with anxiety.

The next day I woke up and took the next dose of Jdtic at 10am. I woke up and had
breakfast. I started to watch television. I couldn't stop laughing. I was in a great
mood. I was laughing, talking to the television. I was talking and joking with my
friends through text messages. I went out for lunch with with my only close friend
left. I kept making her laugh. It was wonderful. I've spent my whole adult life not
being able to touch anyone emotionally. Now I can make people laugh. I started to
see the punch line. I started to become really funny. That day at work. I started to
have these really brief, weak emotions. They were really weak and confusing. But I
was really happy to have them. I started to feel touched by music. I felt driven to
sing along with the music. That day I also caught myself looking at a women's
breast. I started to want to look at her body. I never do that. I usually do not
even notice women anymore. My memory also improved. I usually can't remember any of
the streets. That day I remembered all of them and thought of a plan of the best way to
get there, instead of using a gps.

The next week I planned days out with all my old friends. I wanted to be warm and
try to make them feel loved, and make them laugh. I was trying to make up for being
a cold emotionless person to them. I also went to spend time with my grandfather. My
grandfather is dying. I was too messed to go and see him. I tried my best to be warm
and affectionate to him.

The last few days of the trial. I started to have moments where I felt like my life
had a sense of urgency. I felt like I had to do things. I felt like I had to go home
and read my science books. I'm not sure if I would call it motivation. I just had
these moments where I really wanted to find my vocation in life. I was going to
college for chemical engeneering before I got sick. I just kept having this urgent
feeling that I wanted to finish.

JDTic was very helpful. I still had problems, but I was slowly starting to feel
better. I'm not sure what would happen if I continued to take it. I would love to
find out. I hope that I was helpful. I'm a little tired. I hope I remembered
everything

 

[Funky Buddha]

Quote from http://www.bluelight.ru/vb/threads/593319-JDTic-The-first-orally-active-kappa-antagonist

 

[odisa]

I think it would be nothing like Salvia, considering it is theoretically the exact opposite.
Thanks for posting that quote. Totally forgot about it. Seems to be the only report other than David Pearce's.

 

[Guest]

If Naloxone and Naltrexone can snap some people back to reality, then I don't see why something like JDTic couldn't help snap some people back to reality.

 

[Funky Buddha]

Well I'm pretty confident in this stuff anyway, I think its mechanism of action would be to pull your subconscious thoughts through into your conscious so you end up being able to resolve them and so you come to see how not that much of an issue they are. I'm not quite sure but all I know is, it must also have anti-psychotic properties that would also benefit DP/DR patients as JDTic, as odisa said has the complete opposite effect and salvia divinorum causes psychosis.

If you guys don't want to try it then me and odisa will. If you are interested in trying it then good but it's best to start of with something like 1mg, take a day break then go to 2mg and take a day break etc until you find the correct dose for you. I think the highest dose ever recorded was 10mg or something like that according to jdtic.com.

 

[missjess]

Meh. The heart issues seem rather benign, moreover transient. Essentially a non-issue IMO.
Not yet missjess, but I plan to.

Please keep us informed if u do!!!

I wonder if it could snap people back into reality...would we experience anxiety once being snapped out of dissociation? ...

 

[Funky Buddha]

Please keep us informed if u do!!!

I wonder if it could snap people back into reality...would we experience anxiety once being snapped out of dissociation? ...

Well, I think it depends on how bad your DP/DR is. All I know is when I came out of it once before I did suffer from some anxiety because everything seemed "new" to me as to say. It was hard getting used to the vision but even if you do it should subside after awhile anyway. You'll get used to it.

 

[odisa]

*inviting derp to topic*

 

[missjess]

Well, I think it depends on how bad your DP/DR is. All I know is when I came out of it once before I did suffer from some anxiety because everything seemed "new" to me as to say. It was hard getting used to the vision but even if you do it should subside after awhile anyway. You'll get used to it.

How did u get out of dpdr ? From this drug ??

 

[Funky Buddha]

No. Sometimes, like maybe once or twice a year everything goes back to normal. The longest my DP/DR has gone away for is three days, then it came back. All I remember doing the day before is going to the beach with my friends in the sun, drinking a lot of water and coke and just talking. I walked home feeling really anxious, then the next day I was DP/DR free. :L although, I still had a bit of confusion going on.

 

[odisa]

I find it odd not more people are interested in this..
Funky Buddha; are you going to try NSI-189 as well?
There seem to be reports of improvements in autobiographical memory retrieval as well as formation.

 

[AMUNT]

so many questions

Where can i get it if im in Europe? is it illegal? addictive? in what form do you take it..? price?

 

[odisa]

To clarify once more:

This substance is currently NOT available via your doctor or any common alternative routes.
It MAY be illegal depending on your country's analogue acts (due to it being an opioidergic drug), but it's unlikely to be so.
It is NOT addictive.
It's meant to be taken sublingually (under the tongue) or swallowed orally.
Price depends on how many people show interest in buying. The more people who buy, the cheaper it gets.

 

[AMUNT]

anyone that has taken it yet can testify..?

 

[AMUNT]

BTW: when is it expected to be released?

 

[odisa]

There have only been 2 people on earth who have posted their experiences online; one of which seems to have questionable validity to them. Due to benign complications in preliminary trials, a study-stopping rule was implemented, hence research has been discontinued, or at least suspended. JDTic is unlikely to be available via the usual methods (doctor) this decade.