I wouldn't worry about a Biblical end of the world. Rather I would worry about a purely scientific natural phenomenon that would wipe out the human race while leaving the earth just fine. We aren't the Earth, we're just animals like any other living thing on this giant rock.
Its funny when I hear, specifically about bird flu. The CDC, WHO, and other health officials are saying that a pandemic is inevitable, not a matter of if it will happen but when it will happen. Many countries, are not ready. The united states is saying that it plans more of a military response since drug companies are too greedy to spend money on development of vaccine. And even if a vaccine was development theres no guarantee that it would work. The net result of a flu outbreak would be major cities under martial law, rioting, mass death, large groups of people being quarantined and all that fun stuff. Ballpark figures are 5 to over 200 million people killed worldwide. What the disease doesn't kill the resulting economic depression and disruption of society may.
But then again it might not happen during our lifetime, and we may dodge a bullet. That just leaves global warming, war, terrorism, running out of oil, hurricanes, earthquakes, etc.
Don't worry though just go back to watching TV (NOT CNN) and forget about it like I attempt to do.