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It was one of the first natural anti-psychotic discovered sometime in the 1950's and has been used and still used in India for schizophrenia or what they call there "madness".It also contains the chemical called reserpine which is used for high blood pressure.Most doctors dont know about it or they dont care since it's "herbal".I did some genetic testing and it is believed that I have a slow working enzyme that breaks down dopamine, serotonin etc...which means I actually have enough but my brain cannot properly break them down for use.This enzyme is related to MAO-A.I did lots of research and found that actually this herb I mentioned speeds up Mao-a and my body is able to use dopamine and serotonin.An Ssri would not be good for me at all, as confirmed by my trial of St Johns wort.I have noticed that when I tried this rauwolfia herb, my libido became very high, wouldnt that mean that some of the neurotransmitter did their work ? But my main point in this post is that if your doctor recommended an antipsychotic to try and see if it helps with dpdr, you could first try this herb.Actually medical science back then knew how effective it was, but they replaced it with synthetic ones although all medical literaturw says it is as effective as clozapine but without side effects.