i started with panic attacks while been on carbamazipine...... i believe this is what helped to induce the dp/dr....but i have tried ads....a few totally didnt agree with me....really bad effects but now i am on sertainline.....i had a really hard time getting on it.....every symptom i had increased but after about 4 weeks the symptoms all calmed down....i still have dp/dr...and i do believe most ads make your dp/dr feel worse until the initial side effects are over