I had smoked pot countless times, had done mushrooms once and ecstasy about five times. My DP first started when I was 19, and I had a panic attack a night after ecstasy and heavy drinking. It went away after a couple of days but came back about two months later after heavy drinking. Then it started becoming chronic. I'm sure the ecstasy helped trigger the panic attack. My drinking was the worst thing by far. Ever since I was about 14 or 15, I would go out and get absolutely smashed both weekend night. During the summers, I would probably get wasted 3-4 nights a week. Once I was in college, I probably drank 5 nights a week, 3 of which I would get smashed. I had (I guess I still do) problems blacking out. I would at least black out partially half the times I got wasted. I only had 1 other friend who blacked out like I did, so I should have taken that as a sign. A bad thing for me is that my stomach never told me when to stop. I hardly ever threw up, even when I had extended black-out sessions. I'm sure that had a lot to do with my anxiety and probably my DP.