I posted a lengthy rant about Efexor withdrawal on the 'That's Life' forum. While I was on Efexor (150mg) I felt fine....better than fine. No real anxiety and zilcho panic attacks. And no other side effects that I can think of...not even reduced libido (not that I get the chance to use it !!) like I do on Cipramil. However, and it's a big however, the majority of people here will agree that getting off the stuff is a nightmare. A total nightmare. I never felt so ill in my life...so I changed back to Cipramil, which had no withdrawal whatsoever, in my experience, although no quite as effective.
Anyway, if you're prepared to stay on it the rest of you life or put up with the horrific withdrawal (even when it's tapered withdrawal), then go for it. It is definately effective at relieving symptoms of neurotic illness.