I was on Ciprimal for 3yrs and changed to Effexor xl which ive been on for nearly 3yrs....bar a 6month gap inbetween when i came off effexor. It is a good drug for getting rid of most DP symptoms but i still have some bad days. It is a hard drug to wean yourself off but i managed to do it the first time...the key is to do it ever so slowly which should take you a couple of months but my advice is if you need it take it because as a suffer of DP it can save your life...it has saved mine on numerous occassions.