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Discussion Starter · #1 ·
With seperation anxiety it could be anxiety for being away from you parents, sleeping at places without your parents ect. I had seperation anxiety as a child and there are some research pointing towards the risk of developing panic anxiety is 3.times higher if one had separation anxiety as a child. Panic anxiety has been seen as a component in development depersonalization.
 

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My brother was 4 years older than I. My parents would sometimes leave me in his care. I was 5 or 6, and he was 9 or 10. We would visit my cousin who lived in a nearby

neighborhood. I didn't know the area. My cousin was the same age as my brother. My brother, cousin and I would leave my cousin's house to play with

my cousin's friends in his neighborhood. They would huddle up without me, and on signal all run in different directions, leaving me alone in unfamiliar territory.

I would have to resort to asking strangers if they knew where my cousin lived and if they could tell me how to go to his house.

Older siblings can be cruel. Parents don't always act responsibly.
 

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Discussion Starter · #5 ·
The reason I ask about separation anxiety is because it seems to be related to the development of panic anxiety later in adolescence. Many who gets a negative trip on cannabis very often have a history of panic attacks. So, it was just out of interest to see if this element in development of panic attacks was present in some.
 

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Discussion Starter · #6 ·
Regarding rTMS at the right VLPFC a normal coil as seen on the picture can likely stimulate 30% of the right VLPFC. The right VLPFC expands into the brain and is covered by other structures. So, many parts of it can not be stimulated. You need a coil for deep stimulation and Magventure is the only provider who currently makes one that it used in research and some few private clinics. The right VLPFC might not be the correct location. The anterior cingulate and the dorsomedial prefrontal cortex is more likely a candidate. In theory but location could play a role. But deep coil is need for the location.

The small trail done at the VLPFC can be replicated with the equipment as can the angular gyrus trail.
 

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Regarding rTMS at the right VLPFC a normal coil as seen on the picture can likely stimulate 30% of the right VLPFC. The right VLPFC expands into the brain and is covered by other structures. So, many parts of it can not be stimulated. You need a coil for deep stimulation and Magventure is the only provider who currently makes one that it used in research and some few private clinics. The right VLPFC might not be the correct location. The anterior cingulate and the dorsomedial prefrontal cortex is more likely a candidate. In theory but location could play a role. But deep coil is need for the location.

The small trail done at the VLPFC can be replicated with the equipment as can the angular gyrus trail.
is the anterior cingulate and the dorsomedial prefontral cortex stimulated by the ocd coil from brainsway for deep tms?

and how to explain the point from people who responded to the stimulation of the right vlpfc? they used also not a deep coil right?

are there anecdotes where people with dpd responded to the stimulation of anterior cingulate and dorsomedial prefrontal?
 

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Discussion Starter · #8 ·
The role of the right VLPFC is only found by the depersonalization research unit in samples of brain scan other researchers says is to small in size and increases the chances of error. The rTMS was only of 8.patients and not placebo controlled. Others have not supported the role of the right VLPFC but others point more towards the anterior cingulate and the dorsomedial prefrontal. The anterior cingulate and the dorsomedial prefrontal cortex also came out as abnormally active in the depersonalization research units brain scans along with the right VLPFC. Both locations could play a central role. In 2014 is was not technically possible to intervene at the anterior cingulate and the dorsomedial prefrontal as they are to deep. They only had a coil the that go 1.cm into the brain. So, to intervene at parts the right VLPFC was the only option they had for a trial back then. Because there is a very strong obsessive compulsive component in depersonalization of self awareness and monitoring that is very OCD like the activity of the anterior cingulate and dorsomedial prefrontal cortex might be central.

in medicine in general there is a replication crisis. Findings or trails can not be replicated by others in 50% of the cases. In depersonalization research it is likely a similar figure because the trails have often been very small and not placebo controlled. The samples sizes in brain scan are also very small and increases the chances of errors. So, you have to read everything with some moderation and this in mind.
 

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With seperation anxiety it could be anxiety for being away from you parents, sleeping at places without your parents ect. I had seperation anxiety as a child and there are some research pointing towards the risk of developing panic anxiety is 3.times higher if one had separation anxiety as a child. Panic anxiety has been seen as a component in development depersonalization.
Yes, when I was little I used to be really afraid and cry if I didn't see my mother at the gate after school. I recently remembered something I had forgotten about.
One day my parents were late because they had to go to the bank. I remember me walking along the road in the direction of my house crying and looking around at vehicles passing by. One thing that I remember is for a moment there I really considered jumping in front of one of moving vehicles. After a while someone from school who lived near our house saw me walking and dropped me at my house.
This memory seems to make more sense now because now that I know I'm autistic.
 

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Yes, it's known that separation anxiety, also attachment disorder which can be related, can be a precursor to later mental health problems like panic disorders and dissociation.

I certainly had that, as my mum was unhappy and distant as she was unwell and the marriage bad, and once when I was about eight she told me she and dad might divorce which gave me this desolate feeling. So I always had that anxiety as far back as I can remember.
 

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Born with it yes, I was afraid to sleep alone. Afraid to go to school on my own, afraid of doing sports. Afraid of making choices. I was basically afraid of life since a young age.
 

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Discussion Starter · #14 ·
The ideal set-up will look like this video where the dorsomedial prefrontal cortex is stimulated in depression. The dorsomedial prefrontal cortex along with the anterior cingulate is also active in depersonalization so a similar setup could likely be used in depersonalization. In the video a deep coil is used along with neuronavigation from Localite. It is a research facility.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692428/
 

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Just to follow up on your original question: Yes, I also did have seperation anxiety. I remember having it especially in the evening when I was waiting for my mother or in the kindergarten.

By the way, I once tried hypnotherapy (only 1 session because I didn't really believe in its effectiveness back then) and the practitioner brought me back to the moment when my DPD started (it was in the middle of an ordinary day, without panic attack or similar) and then "asked my subconscious mind" what the reason for my symptoms would be. In trance, I answered with a story about me being a young child in a fight with my mother where she was walking faster than me in a city center and I was afraid of losing her in the streets. I never took the whole thing serious because I had the feeling that the hypnosis practitioner "primed" me before the session and that was the reason for me remembering this story. But of course, I can't be sure.

Thinking about the whole aspect..., why is (clinical) hypnosis therapy not a bigger thing in the treatment of DPD? Emotional detachment and the possible causes and triggers for DPD look like they would be a good approach in clinical hypnotherapy (if done correctly and by trained professionals) as most of it lies in the subconscious. Anybody here with experience of further knowledge about this?
 
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