I found Cipramil very helpful and it got me back to my normal self after years of Anxiety and Depression. I felt that a feeling that I had lost a long time ago returned. It was amazing. I came of it after a few months because I didnt feel myself and tried St Johns wort and was back on the slippery slope downwards. I went back to the Doctor who re prescribed Cipramil for me. This time I found that it didnt have the same effect as before. Not one bit actually. Does anyone think that this may be because I had'nt long come of St John's Wort. I've also tried Effexor but found that that did'nt help much either. I no longer take any medication apart from Vitamins and Minerals but have found that my dp is now worse than ever. Help!