I've noticed most of yalls DP is drug induced. The only thing I've done was marijuana twice at age 15 (I just turned 19 now). And my derealization (24/7) didn't start until 2 months ago, so the smoke had no effect on me after all these years. But I've had dysthymia (long term chronic depression), moderate OCD, and panic/anxiety for the last 2 years or so. But my anxiety has been extremely high in the last 3 months and I was on Xanax for a couple weeks and got off 5 days before my DR started. So can those things alone cause 24/7 DP or DR? And is there anybody else who's DP was just plain panic/anxiety induced and not associated with drugs rather than perscription ones?