The 5HTP makes me feel very tired. So I have stopped taking it. I thinkink you are really suppposed to take it in the evening. The most importnat thing is to stop thinking that you constantly have a problem, because that makes things worse. I am feeling so much better than I was by thinking its just my thoughts that keep me in this fame of mind nothing more. Read 'Stop thinking and Start living ' by Richard Carlson. Best book I have ever read. If have absolutely nothing to lose by geting it. This has given me the greatest help. Let me know how it goes.