After I read you post I found this article. Problem is, I'm not sure I understand what it is saying. I underlined what I think is the main point so that you don't have to read a bunch of boring stuff if you don't want. Are they saying that our cortisol levels are too low or too high? I honestly can't tell. That'd be amazing if DP was cured by some fat blocker "As seen on TV".
Stanton BR. David AS. Cleare AJ. Sierra M.
Lambert MV. Phillips ML. Porter RJ. Gallagher P. Young AH.
(2001) Basal activity of the hypothalamic-pituitary-adrenal axis in patients
with depersonalization disorder. Psychiatry Research. 104(1):85-9
Depersonalisation disorder may occur during severe anxiety or following a
traumatic event, suggesting a possible role of stress hormones.
This study investigated basal activity of the hypothalamic-pituitary-adrenal
(HPA)axis in patients with depersonalisation disorder. Salivary cortisol levels
were measured at four time-points over 12hours in patients with
depersonalisation disorder (N=13), major depressive disorder
(MDD, N=14)and healthy controls (N=13). Beck Depression
Inventory scores were significantly higher in depersonalised subjects
than controls, while MDD subjects demonstrated higher scores than both groups.
Basal cortisol levels of depersonalised subjects were significantly lower
than MDD subjects but not healthy controls.
These results point to reduced basal activity of the HPA axis in
depersonalisation disorder. This pilot study supports the distinction between
depersonalisation disorder and major depressive disorder which should
be examined in a larger sample.