I have been having derealization for 20 years now, and some depersonalization mostly in the first 10 years and it tended to fade away.
What is puzzling me is that the vast majority of people say that their symptoms are correlated with anxiety or terrible panic attacks, and it doesn't seem to be the case for me. I do have a tendency to be anxious, and at times I have had really bad anxiety, like a few years ago when it was so bad that my immune system shut down, my digestion stopped completely for 2 days, I felt cold non-stop or some times I was so anxious that I thought I could not survive this. And at other times I felt no anxiety at all, everything was manageable, I felt very ok. And in both these kind of circumstances my derealization was absolutely constant. Anxiety did not make it worse, and absence of anxiety did not make it better.
But some things have helped me recently. I have been on Sertraline (SSRI) for 4 days, and I felt like my derealization was almost completely gone. I had to stop because of too strong side effects though, and some mild auditory hallucinations. And so the derealization came back. I am now on a low dose of Risperidone and Lithium, and the derealization is just slightly lower than normal, but barely noticeable difference.
I realized I have a kind of obsessive way of thinking, where every thought I have comes as a form of imaginary conversation with someone. Every thought I have, all the time. I realized this was a kind of way to imagine having acknowledgment (or recognition is the right word?), and one day I tried to take each thought that I was having and just put it back in context of this need of acknowledgment, that this was all imaginary, that the real meaning of the thought is a need of acknowledgment. As I did this, I felt a very strong rush of "re-realization", like a flash. I have never had this before in all this time. But then it was gone and impossible to make it happen again. I had another rush like this in another similar circumstance but it is maybe a story for another time.
I am kind of annoyed that I don't have obvious anxiety reasons to focus on to get rid of the DR. I was wondering if anybody had something similar (no correlation with anxiety) and I would be interested to know if you too have some kind of obsessive thinking patterns, and what helped you.