'increased synaptic dopamine such as the amphetamines, methylphenidate, pemoline, bupropion, etc. seemed to be beneficial for depersonalization.1'
From the case report of methlphendidate.
+1. When I was taking it I thought it had cured me. But then I started getting bad (I think hypertensive) headaches as well as tremors from the ritalin. I had to stop. I took a genomind test and found out that I have a mutation in an enzyme that breaks down dopamine in the PFC and mine doesn't function well so I have higher PFC dopamine.
Found that interesting and also interesting that ritalin was so helpful.
Also, can you expand on your commentary on HPA?
I also suggest you check out tineptine as it related to hippocampal atrophy as well as semax.